Cheerleading has been an integral part of St. Joe's since the school's inception. The school offers both varsity and junior varsity cheerleading squads. Tryouts are open to any student.The varsity squad cheers at all varsity football and home boys basketball games. The junior varsity squad cheers at home contests for boys JV basketball and girls varsity basketball.
The varsity cheerleading squad has a long standing tradition of excellence in the state as they were awarded the 2014 and 2015 Class M State Champions as well as the Class M State Runner-Up in 2013 and 2010. Additionally, they were award National Champions in the Super Large Varsity division at the 2015 Cheer Ltd. Canam Nationals. They also have been named FCIAC Grand Champions three times in 2000, 2008 and 2009.